LGD-4033, also called Ligandrol, has been studied briefly in healthy men. Body-composition findings should be read alongside hormonal and lipid changes.
What did the trial show?
A 21-day study in 76 men found increased lean mass without a significant strength advantage over placebo. Testosterone, SHBG and HDL also changed in a dose-dependent manner. Reference: LGD-4033 trial in healthy men
Why does mass differ from strength?
Body-composition instruments and strength tests measure different outcomes. Improvement in one does not establish the same improvement in another or necessarily improve daily function.
Does recovery of laboratory values settle safety?
Recovery of selected measurements during one follow-up period cannot establish safety in every person or a different exposure setting. Read the study boundaries alongside its results.
US FDA warns that SARMs are unapproved drugs and may cause serious health problems. FDA: SARMs
Frequently asked questions
Has LGD-4033 been studied in humans?
Yes. The example discussed here is a short trial in healthy men.
Does it settle long-term outcomes?
No. The exposure and follow-up were too short to answer all long-term questions.
How should this article be used?
Use it to identify the substance, understand what the cited research measured, and prepare questions for a qualified clinician. It is educational information, not an individual treatment plan.