{"id":9786,"date":"2024-10-12T17:10:15","date_gmt":"2024-10-12T17:10:15","guid":{"rendered":"https:\/\/www.musclestationth.com\/?p=9786"},"modified":"2026-09-20T08:23:30","modified_gmt":"2026-09-20T08:23:30","slug":"sarms-%e0%b9%80%e0%b8%9e%e0%b8%b4%e0%b9%88%e0%b8%a1%e0%b8%81%e0%b8%a5%e0%b9%89%e0%b8%b2%e0%b8%a1%e0%b9%80%e0%b8%99%e0%b8%b7%e0%b9%89%e0%b8%ad-%e0%b8%a5%e0%b8%94%e0%b9%84%e0%b8%82%e0%b8%a1%e0%b8%b1","status":"publish","type":"post","link":"https:\/\/www.musclestationth.com\/en\/sarms-%e0%b9%80%e0%b8%9e%e0%b8%b4%e0%b9%88%e0%b8%a1%e0%b8%81%e0%b8%a5%e0%b9%89%e0%b8%b2%e0%b8%a1%e0%b9%80%e0%b8%99%e0%b8%b7%e0%b9%89%e0%b8%ad-%e0%b8%a5%e0%b8%94%e0%b9%84%e0%b8%82%e0%b8%a1%e0%b8%b1\/","title":{"rendered":"What are SARMs? Studied benefits and health effects"},"content":{"rendered":"<p>SARMs are selective androgen receptor modulators. Researchers study effects on tissues such as muscle; benefits, hormonal changes and other health effects depend on the individual compound and trial. MK-677 is a different class.<\/p><section id=\"additional-compound-guides\"><h2>More individual substance guides<\/h2><div class=\"ms-education-grid\"><a class=\"ms-education-card\" href=\"https:\/\/www.musclestationth.com\/en\/ostarine-mk-2866-evidence-guide\/\"><span class=\"ms-education-tag\">Ostarine \/ MK-2866<\/span><h3>Ostarine (MK-2866): understanding enobosarm evidence<\/h3><span class=\"ms-education-read\">Read article \u2192<\/span><\/a><a class=\"ms-education-card\" href=\"https:\/\/www.musclestationth.com\/en\/ligandrol-lgd-4033-evidence-guide\/\"><span class=\"ms-education-tag\">Ligandrol \/ LGD-4033<\/span><h3>Ligandrol (LGD-4033): lean mass and hormone findings<\/h3><span class=\"ms-education-read\">Read article \u2192<\/span><\/a><a class=\"ms-education-card\" href=\"https:\/\/www.musclestationth.com\/en\/rad-140-evidence-guide\/\"><span class=\"ms-education-tag\">RAD-140<\/span><h3>RAD-140: human research and its limits<\/h3><span class=\"ms-education-read\">Read article \u2192<\/span><\/a><a class=\"ms-education-card\" href=\"https:\/\/www.musclestationth.com\/en\/andarine-s4-evidence-guide\/\"><span class=\"ms-education-tag\">Andarine \/ S4<\/span><h3>Andarine (S4): separating animal and human evidence<\/h3><span class=\"ms-education-read\">Read article \u2192<\/span><\/a><a class=\"ms-education-card\" href=\"https:\/\/www.musclestationth.com\/en\/s-23-evidence-guide\/\"><span class=\"ms-education-tag\">S-23<\/span><h3>S-23: SARM research and reproductive questions<\/h3><span class=\"ms-education-read\">Read article \u2192<\/span><\/a><\/div><\/section><nav aria-label=\"Health article series\"><p>In this series: <a href=\"https:\/\/www.musclestationth.com\/en\/steroid-sarm-peptide-blood-health\/\">Browse all five topics<\/a><\/p><\/nav><h2>What are SARMs?<\/h2><p>Selective androgen receptor modulators are studied for effects at androgen receptors, including effects on tissues such as muscle. Selective describes an intended pattern of activity; it is not a guarantee of no hormonal or other organ effects. See the <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4111291\/\" rel=\"noopener\">LGD-4033 study<\/a>.<\/p><h2>Which benefits have been measured?<\/h2><p>A <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4111291\/\" rel=\"noopener\">21-day LGD-4033 trial in 76 healthy men<\/a> found increased lean body mass as well as changes in testosterone and HDL. The study helps describe short-term biological responses. It does not answer long-term health questions.<\/p><h3>Lean mass is not automatically strength<\/h3><p>When a report says lean mass increased, ask whether it also demonstrated improvements in strength, everyday function or quality of life. A body-composition result should not stand in for an outcome the study did not establish. Findings for one compound also do not validate the whole SARM class.<\/p><h2>What limits the claims?<\/h2><p>The <a href=\"https:\/\/www.fda.gov\/drugs\/fraudulent-products\/certain-bodybuilding-products-put-consumers-risk-heart-attack-stroke-serious-liver-damage-and-more\" rel=\"noopener\">U.S. FDA<\/a> states that SARMs are not approved by that agency and warns of potentially serious liver, cardiovascular and reproductive effects. This describes U.S. status; it does not establish the registration of a product in Thailand.<\/p><p>A controlled human study, an animal experiment and an advertisement provide different kinds of evidence. Before accepting \u201csafer\u201d as a conclusion, look for a direct comparison, the safety outcomes measured and the length of follow-up.<\/p><h2>Four questions for reading a study<\/h2><ol><li>Who was studied: healthy people, patients or animals?<\/li><li>What was measured: lean mass, strength or a health outcome?<\/li><li>How long did observation last?<\/li><li>What appeared alongside the benefit: hormonal, lipid or symptom changes?<\/li><\/ol><h2>Preparing for a health discussion after exposure<\/h2><p>Record the substance or product name, exposure timeline, changing symptoms and previous laboratory results. Seek prompt assessment for chest pain, shortness of breath or jaundice, as described in the <a href=\"https:\/\/www.fda.gov\/drugs\/fraudulent-products\/certain-bodybuilding-products-put-consumers-risk-heart-attack-stroke-serious-liver-damage-and-more\" rel=\"noopener\">FDA safety information<\/a>. Appropriate testing and follow-up depend on individual history.<\/p><h2>Is MK-677 a SARM?<\/h2><p>No. MK-677 is a nonpeptide ghrelin-receptor agonist, whereas SARMs concern androgen receptors. Read the <a href=\"https:\/\/www.musclestationth.com\/en\/mk-677-ibutamoren-evidence\/\">MK-677 guide<\/a> for its own evidence and glucose-related questions. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18923064\/\" rel=\"noopener\">Primary receptor research.<\/a><\/p><section id=\"faq\"><h2>Frequently asked questions<\/h2><h3>Does selective mean no side effects?<\/h3><p>No. Selective activity does not mean an absence of hormonal, liver or other systemic effects.<\/p><h3>Can LGD-4033 research validate every SARM?<\/h3><p>No. The compound, population, outcomes and follow-up of each study must be considered separately.<\/p><h3>Is MK-677 a SARM?<\/h3><p>No. MK-677 acts at the ghrelin receptor and belongs to a different class from SARMs.<\/p><\/section><nav class=\"ms-education-related\" aria-labelledby=\"ms-read-next-title\"><h2 id=\"ms-read-next-title\">Read next<\/h2><div class=\"ms-education-grid\"><a class=\"ms-education-card\" href=\"https:\/\/www.musclestationth.com\/en\/mk-677-ibutamoren-evidence\/\" style=\"--ms-topic-color:#186d80\"><span class=\"ms-education-tag\">HEALTH & RESEARCH<\/span><h3>What is MK-677? Ibutamoren evidence and differences from SARMs<\/h3><span class=\"ms-education-read\">Read the guide <span aria-hidden=\"true\">\u2192<\/span><\/span><\/a><a class=\"ms-education-card\" href=\"https:\/\/www.musclestationth.com\/en\/blood-tests-health-guide\/\" style=\"--ms-topic-color:#186d80\"><span class=\"ms-education-tag\">HEALTH & RESEARCH<\/span><h3>Blood-test overview<\/h3><span class=\"ms-education-read\">Read the guide <span aria-hidden=\"true\">\u2192<\/span><\/span><\/a><a class=\"ms-education-card\" href=\"https:\/\/www.musclestationth.com\/en\/how-to-read-peptide-research\/\" style=\"--ms-topic-color:#186d80\"><span class=\"ms-education-tag\">HEALTH & RESEARCH<\/span><h3>How to read peptide research: from cells and animals to people<\/h3><span class=\"ms-education-read\">Read the guide <span aria-hidden=\"true\">\u2192<\/span><\/span><\/a><\/div><p class=\"ms-education-back\"><a href=\"https:\/\/www.musclestationth.com\/en\/steroid-sarm-peptide-blood-health\/\">Back to the Knowledge Hub \u2192<\/a><\/p><\/nav>","protected":false},"excerpt":{"rendered":"<p>SARMs are selective androgen receptor modulators. Researchers study effects on tissues such as muscle; benefits, hormonal changes and other health effects depend on the individual compound and trial. MK-677 is a different class.<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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href=\"https:\/\/www.musclestationth.com\/en\/category\/%e0%b8%9a%e0%b8%97%e0%b8%84%e0%b8%a7%e0%b8%b2%e0%b8%a1%e0%b8%97%e0%b8%b5%e0%b9%88%e0%b8%99%e0%b9%88%e0%b8%b2%e0%b8%aa%e0%b8%99%e0%b9%83%e0%b8%88\/\" rel=\"category tag\">\u0e1a\u0e17\u0e04\u0e27\u0e32\u0e21\u0e17\u0e35\u0e48\u0e19\u0e48\u0e32\u0e2a\u0e19\u0e43\u0e08<\/a>","rttpg_excerpt":"Read SARM-related physique and performance claims critically, without goal-based rankings or drug regimens.","_links":{"self":[{"href":"https:\/\/www.musclestationth.com\/en\/wp-json\/wp\/v2\/posts\/9786","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.musclestationth.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.musclestationth.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.musclestationth.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.musclestationth.com\/en\/wp-json\/wp\/v2\/comments?post=9786"}],"version-history":[{"count":5,"href":"https:\/\/www.musclestationth.com\/en\/wp-json\/wp\/v2\/posts\/9786\/revisions"}],"predecessor-version":[{"id":12291,"href":"https:\/\/www.musclestationth.com\/en\/wp-json\/wp\/v2\/posts\/9786\/revisions\/12291"}],"wp:attachment":[{"href":"https:\/\/www.musclestationth.com\/en\/wp-json\/wp\/v2\/media?parent=9786"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.musclestationth.com\/en\/wp-json\/wp\/v2\/categories?post=9786"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.musclestationth.com\/en\/wp-json\/wp\/v2\/tags?post=9786"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}